Gastroenterology

UniPath provides quantitative testing for Epidermal Growth Factor Receptor (EGFR). Determination of tumor EGFR status is necessary to begin therapy with Erbitux®.
Quantitation is performed using the Chromavision Automated Cellular Imaging System (ACIS) platform, which eliminates inter-observer variability. Testing is performed daily on paraffin section material.

UniPath provides screening for Microsatellite Instability by performing immunohistochemical testing on tumor and normal tissue for DNA repair enzymes MLH1 and MSH2. Quantitation is performed using the Chromavision Automated Cellular Imaging System (ACIS) platform, which eliminates inter-observer variability. Testing is performed daily on paraffin section material.

UniPath offers a colon cancer profile performed on invasive colon carcinomas that includes p53, p21 (WAF1/CIP1), Ki67, p27/kip1 and thymidylate synthase (TS). Quantitation is performed using the Chromavision Automated Cellular Imaging System (ACIS) platform, which eliminates inter-observer variability. Testing is performed daily on paraffin section material.

UniPath offers quantitative assessment of CD117 staining for Gastrointestinal Stromal Tumors (GIST). Accurate testing for CD117 is critical for determining success of Gleevec® therapy.

UniPath maintains a large library of antibodies for tumor characterization of tumors.

Consultation services also available.

Gastroenterology sample report>>